HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- How many is too many? Exploring the toxic CAG threshold in the Huntington’s disease brain
- Cry your eyes out: detecting huntingtin in tears
- The director’s cut: how CAG repeats change the editing of genetic messages
- Making babies: having a family, the HD way
- Understanding expansions at the single cell level
Literature
- Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease
- Exploring potential developmental origins of common neurodegenerative disorders
- HYPK: A marginally disordered protein sensitive to charge decoration
- Exploring neurodegenerative disorders using advanced magnetic resonance imaging of the glymphatic system
- Endogenous mutant Huntingtin alters the corticogenesis via lowering Golgi recruiting ARF1 in cortical organoid
News
- Researchers find depression, CVD partly develop from same gene module - BizzBuzz
- Sage reports strong sales of new postpartum depression drug in Q1 - The Business Journals
- Sage Therapeutics stock target cut on Zurzuvae launch - Investing.com
- Huntington's Disease Society of America's (HDSA) Team Hope Walk Across Iowa Returns May 4
- Toronto theatre premiere will use video games to explore Huntington's disease